BMSE Seminar:"Epigenome and 3D chromosome"


Prof. Wei Wang, UCSD, Chemistry. Host: Norbert Reich

Date and Location

Wednesday April 05, 2017 11:00am to 12:00pm
Elings 1601


Abstract: The human genome is tightly packaged into chromatin and forms complex structures of which the functional outputs, such as gene expression, depend on local chromatin states and chromatin three-dimensional organization. Epigenomic modifications and chromatin interactions are tightly associated. An emerging question is to understand the relationship between structure and function of the chromosome. In this talk I will discuss our recent efforts of connecting the epigenomic modifications to the chromatin structure and identifying the protein complexes mediating chromatin looping.